Pharmacotherapy

Monday, March 26, 2007

Suicide risk factors

By, Heather Muller, The Eureka Reporter, February 25, 2007

On Feb. 3, 2006, Michelle Roskopp lost her long battle with drug addiction, with mental illness, with physical illness and with the circumstances of her short, troubled life. She committed suicide a month before her 37th birthday — a death her mother said “could have been delayed but probably not prevented.”

Why did Michelle die?

The story goes that when Michelle died, her boyfriend was threatening to kill himself after learning she had prostituted herself to buy crack cocaine, according to Michelle’s mother, Fortuna resident Susie Spitzer.

“She said to him, ‘What are you going to do, how are you going to do it?’ So he took the gun and put it in her mouth. And she said, ‘What are you going to do next?’ and he said, ‘Pull the trigger.’ He started screaming at her, just screaming for her to pull the trigger. ‘Pull the trigger, pull the trigger,’” Susie said.

“So she did.”

Though Michelle’s suicide came as a shock to those who knew her, her death at the age of 36 was not entirely unexpected.

“She was sick,” Susie said, “really sick. At that point, she weighed only about 85 pounds.”

Not long before Michelle’s death, her mother received a phone call from a Las Vegas hospital saying that Michelle had just walked out of the emergency room, against the advice of a physician.

She had been diagnosed with extremely severe lupus, was suspected of having hepatitis B and C, and had refused a test for HIV — all of which her mother, a 30-year registered nurse, believed Michelle had.

Certainly physical illness wasn’t Michelle’s only serious problem. She had been diagnosed with schizophrenia as a child, and in recent years had lost her marriage, her job, her home and her two children to habitual drug use.

“I want to emphasize that although she did have some emotional problems, she was not always a bad person,” her mother said. In fact, she was a graduate of the University of Nevada, Las Vegas, and worked as a designer for a major Las Vegas casino. She was by all accounts a good mother to her children.

That was before the drugs.

“She turned into a crack whore,” Susie said. “Saying that makes me want to vomit, but it’s an honest statement.”

So what killed Michelle Roskopp?

The short answer is that she did. But the long answer could be even more troubling.

According to reports from the Humboldt County Coroner’s Office, as much as 60 percent of the 141 people who died from suicide in Humboldt County from 2002 through 2006 suffered from a diagnosed mental illness — depression was most common, followed by bipolar disorder and schizophrenia.

Drugs and/or alcohol were named as factors in 45 percent of suicides during the same period, with prior attempts and/or threats documented in 41 percent of deaths.

Isolation — one of the most common explanations of suicide in sparsely populated rural areas — was identified in less than one-fourth of all deaths.

But probably the most startling statistic gleaned from the coroner’s reports was the high number of suicides in which serious chronic or fatal illness was said to be a factor.

For 61 people — 43 percent — at least one of a list of dire, debilitating conditions was named, ranging from chronic pain to terminal cancer.

Among the risk factors regularly documented in coroner’s reports were five circumstantial or event-based factors, including difficulties relating to various losses — of a relationship, of status and even freedom stemming from serious criminal charges, of a place to live, of a job or of a loved one.

Michelle had almost all of these things working against her. Her risk assessment, if such a thing is even possible, was off the charts.

But in many other suicides in which medical illness was said to be a factor, the person who died did not appear to be otherwise at risk.

According to coroner’s reports, the average number of 10 risk factors in suicide deaths in Humboldt County was three.

But of the dozens of suicide deaths in which only one or two risk factors were identified, the overwhelming majority — more than 60 percent — were chronically or terminally ill.

That wasn’t the only difference between the two groups.

The seriously ill also tended to kill themselves in noticeably different ways. Gunshot deaths were slightly more common in that group, and hanging deaths — which accounted for 23 percent of the deaths of healthy individuals — were practically nonexistent among the physically ill.

And while people without medical problems were almost eight times more likely to hang themselves than those with, the second group was four times more likely to die from a prescription drug overdose, a means readily available to the seriously ill.

Humboldt County Director of Health and Human Services Phillip Crandall said that discussion about the causes of suicide tends to center around mental illness — and not for nothing. Virtually every major suicide organization in the country states that probably 90 percent of all suicide deaths involves some type of mental illness, diagnosed or otherwise.

But, Crandall said, “It needs to be remembered that mental illness is not the only thing that moves people to suicide.”

Researchers agree.

Mental illness can interfere with rational thought processes, they say, and drug or alcohol abuse can increase impulsivity. Prior threats or attempts can indicate whether suicide is within the range of possibility for a particular person, and isolation can limit communication with those who might offer solace.

Similarly, event-based risk factors and losses can trigger a suicidal episode — but researchers consider these not so much an explanation of suicide as an opportunity for suicide to occur.

Noted expert E.S. Shneidman did find some commonalities among all suicides.

According to his research, the common goal is a cessation of consciousness, and the common stimulus an “intolerable psychological pain.”

Perhaps most important is the common emotion of suicide — what Shneidman described as a combination of hopelessness and helplessness, a condition that dominated the years leading up to Michelle’s death.

“I don’t think she thought she had a whole lot of options left in life,” her mother said. “It’s like she painted herself into a corner. She felt helpless. She felt hopeless. I think she thought she had burned all her bridges. They say nothing’s over until it’s over, but maybe that wasn’t the case with her.”

It’s difficult to imagine anything more likely to cause hopelessness and despair than the knowledge of a slow and painful terminal illness.

“I don’t think she thought she could come back from that,” Susie said.

And Susie didn’t think so either.

“I just always assumed she would come home when she got sick enough to die, and I would take care of her. That’s what I thought would happen. That’s what I thought our happy ending would be.”

Instead, a few weeks before Michelle’s death, Susie received a letter from her daughter.

“I’m not going to stay away from you any more,” it stated in part. “I need and love you too much. I’m so sorry for all the pain I’ve caused. I love you very much, Mom. Love, Shelley.”

Source: http://www.eurekareporter.com/ArticleDisplay.aspx?ArticleID=20925

A shot in the arm...or a headache for the law?

By, The straits Times, March 24, 2007

Malaysia: The "harm reduction" pilot programme introduced in 2005 for intravenous dadah users is a resounding success, at least as far as the Health Ministry is concerned.

Deputy director-general of Health Datuk Dr Ramlee Rahmat said the majority of the addicts involved in the pilot project had kicked the habit.

He said the ministry will start recruiting more addicts in new areas.

He said the ministry had an understanding with the police and the anti-drug agency on the expansion of the programme and on areas which will be out of bounds to raiding parties when the programme is on.

The ministry will, however, not stop the police from arresting addicts involved in the programme caught in criminal activities or dadah abuse outside the programme area.

"The police have their duty to arrest those who are a threat to national security."

The primary thrust of harm reduction is a combination of dadah substitution therapy using methadone and a needle and syringe exchange programme.

The idea of addicts returning used needles is to prevent the spread of HIV/AIDS through contamination.

The ministry’s needle exchange programme manager Datuk Dr Faisal Ibrahim said all addicts in the programme received counselling to ensure they did not return to the habit or share needles.

Some 100-odd addicts in the needle exchange programme have since decided to switch to methadone.

"Our aim is to make sure they fully understand the programme and not violate the rules and regulations stipulated to them."

He said a meeting was held bimonthly between the stakeholders including the police to get feedback on the situation.

According to World Health Organisation figures, the success rate of harm reduction programmes is usually aro- und 70 per cent.

Dr Faisal said there were some 1,200 dadah addicts involved in the needle exchange programme in Johor, Penang and Kuala Lumpur.

"Feedback showed that 60 per cent of those who participated in the needle exchange programme returned used needles. This is good."

On addicts switching to methadone, he said this was a clear sign that the harm reduction programme had ach- ieved its objectives.



THE NEGATIVE


POLICE feel the "harm reduction" programme has given them a headache.

Bukit Aman Anti-Narcotics director Datuk Abang Abdul Wahab Abang Julai said the police had to release hundreds of dadah users back to the streets as they were protected under the programme.

"We have to close an eye in the matter although they should by right be arrested. But since it is a government initiative, we have backed the government 100 per cent."

Abang Abdul Wahab said he had completed a paper for submission to the government on the dadah problem and ways to curb the menace.

"There is a lot of money allocated to curb this problem but the money should be used wisely."

He said First World countries practised the needle and syringe exchange progra- mme (NSEP) but were governed by the Dangerous Drugs Act like in Malaysia.

"In Australia, drug addicts are told to come to centres where a medical assistant administers the drug into the addict using a new needle and syringe."

Abang Abdul Wahab said this was good as addicts could not go back to the streets to share the new needles and syringes with their friends or even sell them.

In February last year, the government started distributing free syringes in exchange for used ones and condoms to dadah addicts in Kuala Lumpur, Johor and Penang.

The cabinet allocated RM100 million over five years on top of the RM40 million annual allocation for the "harm reduction" programme which includes NSEP and the methadone programme.

A total of 100 paramedics have also been trained at a cost of RM600,000 to counsel and administer anti-retroviral drugs to patients.


Source: http://www.nst.com.my/Current_News/nst/Saturday/National/20070324083632/Article/local1_html

Monday, March 12, 2007

UN drug watchdog ignores HIV, rights groups say

By, Michelle Nichols, Reuters, February 27, 2007

The U.N. drug control watchdog is hindering efforts to fight the global AIDS pandemic and the agency should be independently reviewed, human rights groups and a former U.N. AIDS envoy said on Tuesday.

The Canadian HIV/AIDS Legal Network, the Open Society Institute and Stephen Lewis, a former U.N. special envoy for AIDS in Africa, accused the 13-member International Narcotics Control Board of enforcing drug policies that ignore public health.

"If I had it in my grasp I would take them out behind the international woodshed and give them an intellectual and rhetorical flogging, the like of which they would never forget," Lewis told a news conference.

A report by the groups said one third of HIV infections outside of Africa were caused by injection drug use and while the U.N. board acknowledged drug use was accelerating the spread of the disease in some countries, it failed to encourage any preventive action.

The report, "Closed to Reason," said the International Narcotics Control Board, established in 1968, had not only ignored the public health implications of drug use, but discredited "effective programs" such as sterile syringe exchanges and the use of methadone as an addiction treatment.

"It's as though the HIV/AIDS conjunction has passed the International Narcotics Control Board right by," Lewis said. "They are aligning themselves with the virus rather than opposing it determinedly."

Lewis, a Canadian, also told of how while he was former U.N. Secretary-General Kofi Annan's special envoy on AIDS in Africa between 2001 and 2006, he voiced support for safe drug injection rooms.

He said the control board complained to Annan about his comments. "The fact that they would write a letter attempting to silence a critic is a demonstration of how out of control the International Narcotics Control Board is," Lewis said.

The Vienna-based International Narcotics Control Board (INCB) is an independent judicial body elected by U.N. members that monitors the implementation of international drug control conventions. A spokesman was not available for comment.

Nearly 40 million adults and children in 2006 lived with HIV, the virus that causes AIDS, with more than 25 million in Africa alone, U.N. figures show.

"Millions at risk of HIV in Eastern Europe and Asia can benefit from drug policy that works in tandem with public health," said Daniel Wolfe, deputy director of the Open Society Institute's international harm reduction development program.

"Alleviation of human suffering is one portion of the international conventions that the INCB has done strikingly little to uphold," he said.
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